| Identification | Back Directory | [Name]
Carbonochloridic acid, 1,1-diMethylethyl ester | [CAS]
24608-52-4 | [Synonyms]
tert-Butyl chloroforMate
ert-butylcarbonochloridate
tert-butoxycarbonyl chloride
Tert-butyl carbonochloridate
Carbonochloridic acid, 1,1-diMethylethyl ester | [Molecular Formula]
C5H9ClO2 | [MDL Number]
MFCD17013431 | [MOL File]
24608-52-4.mol | [Molecular Weight]
136.58 |
| Chemical Properties | Back Directory | [Melting point ]
10 °C (decomp) | [Boiling point ]
3-4 °C(Press: 0.9-1.7 Torr) | [density ]
1.084±0.06 g/cm3(Predicted) | [solubility ]
sol ether, toluene, and most organic aprotic solvents |
| Hazard Information | Back Directory | [Uses]
T-Butyl Chloroformate is used as a reagent for the protection of amino groups, including amino acids.
| [Preparation]
T-Butyl Chloroformate should be prepared from t-butanol or potassium t-butoxide and phosgene shortly before use.
| [storage]
T-Butyl chloroformate should be kept as a solution in anhydrous solvent at low temperature (deep freezer) and for a period of time not exceeding a few days. Decomposition leads to high pressure in the storage vessel. May contain some residual phosgene.
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