| Identification | Back Directory | [Name]
Catharanthine | [CAS]
2468-21-5 | [Synonyms]
18-beta)-lph
catharanthin
CATHARANTHINE
(+)-CATHRANTHINE
CATHARANTHINE(RG)
CATHARANTHINE BASE
Catharanthine Sulphate
CatharanthineSulfateBase
(+)-3,4-Dihydrocoronaridine
(+)-3,4-didehydrocoronaridine
(+)-3,4-Didehydrocoronaridine Tartrate
Methyl (2a,5b,6a,18b)-3,4-didehydroibogamine-18-carboxylate
methyl (2alpha,5beta,6alpha)-3,4-didehydroibogamine-18beta-carboxylate
[2α,5β,6α,18β,(+)]-3,4-Didehydroibogamine-18-carboxylic acid methyl ester
Ibogamine-18-carboxylicacid, 3,4-didehydro-, methyl ester, (2α,5β,6α,18β)-
ibogamine-18-carboxylicacid,3,4-didehydro-,methylester,(2-alpha,5-beta,6-a
Ibogamine-18-carboxylic acid, 3,4-didehydro-, methyl ester, (2a,5b,6a,18b)-
methyl(2-alpha,5-beta,6-alpha,18-beta)-3,4-didehydroibogamine-18-carboxylate
(2a,5,6a,18)-3,4-Didehydro-ibogamine-18-carboxylic Acid Methyl Ester Tartrate
7-Ethyl-9,10,12,13-tetrahydro-6,9-methano-5H-pyrido[1′,2′:1,2]azepino[4,5-b]indole-6(6aH)-carboxylic acid methyl ester | [EINECS(EC#)]
219-586-6 | [Molecular Formula]
C21H24N2O2 | [MDL Number]
MFCD01753356 | [MOL File]
2468-21-5.mol | [Molecular Weight]
336.43 |
| Chemical Properties | Back Directory | [Appearance]
Off-White to Pale Beige Solid | [Melting point ]
138-1400C | [alpha ]
D27 +29.8° (CHCl3) | [Boiling point ]
472.9°C (rough estimate) | [density ]
1.1367 (rough estimate) | [refractive index ]
1.6500 (estimate) | [storage temp. ]
?20°C | [solubility ]
DMSO: soluble5mg/mL (clear solution; warmed) | [form ]
powder | [pka]
6.8(at 25℃) | [color ]
white to beige | [Optical Rotation]
[α]/D +30 to +38° (c=0.5, CDCl3) | [InChI]
InChI=1/C21H24N2O2/c1-3-14-10-13-11-21(20(24)25-2)18-16(8-9-23(12-13)19(14)21)15-6-4-5-7-17(15)22-18/h4-7,10,13,19,22H,3,8-9,11-12H2,1-2H3/t13-,19+,21-/s3 | [InChIKey]
CMKFQVZJOWHHDV-XWQFPIRHNA-N | [SMILES]
[C@]12(C(=O)OC)C[C@]3([H])C=C(CC)[C@@]1([H])[N@](CCC1C4=C(C=CC=C4)NC2=1)C3 |&1:0,6,12,14,r| |
| Hazard Information | Back Directory | [Chemical Properties]
Off-White to Pale Beige Solid | [Usage]
Anticancer | [Usage]
Precursor of Vinblastine-type alkaloids | [Uses]
Anticancer | [Uses]
Catharanthine is an indole alkaloid analog and an inhibitor of TRPM8. | [Uses]
Precursor of Vinblastine-type alkaloids | [Definition]
ChEBI: Catharanthine is an organic heteropentacyclic compound and monoterpenoid indole alkaloid produced by the medicinal plant Catharanthus roseus via strictosidine. It is a bridged compound, an organic heteropentacyclic compound, a methyl ester, a monoterpenoid indole alkaloid, a tertiary amino compound and an alkaloid ester. It is a conjugate base of a catharanthine(1+). | [target]
NO | Calcium Channel | Nicotinic receptor |
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