| Identification | Back Directory | [Name]
1H-Indole-2-carboxylic acid, 5-fluoro-3-[(4-oxo-2-thioxo-5-thiazolidinylidene)methyl]-, methyl ester | [CAS]
2470015-35-9 | [Synonyms]
Anticancer agent 43
1H-Indole-2-carboxylic acid, 5-fluoro-3-[(4-oxo-2-thioxo-5-thiazolidinylidene)methyl]-, methyl ester | [Molecular Formula]
C14H9FN2O3S2 | [MOL File]
2470015-35-9.mol | [Molecular Weight]
336.36 |
| Hazard Information | Back Directory | [Uses]
Anticancer Agent 43 is a potent anticancer agent. Anticancer Agent 43 induces apoptosis by caspase 3, PARP1, and Bax dependent mechanisms. Anticancer Agent 43 induces DNA damage[1]. | [IC 50]
Caspase 3; PARP1; Bax | [References]
[1] Kryshchyshyn-Dylevych A, et al. Synthesis of novel indole-thiazolidinone hybrid structures as promising scaffold with anticancer potential. Bioorg Med Chem. 2021; 50:116453. DOI:10.1016/j.bmc.2021.116453 |
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