Identification | Back Directory | [Name]
JTV 803 | [CAS]
247131-79-9 | [Synonyms]
JTV 803 JTV-803 mesylate NOBZETMXGVAWIM-UHFFFAOYSA-N JTV 803 mesylate,JTV803 mesylate | [Molecular Formula]
C23H31N5O6S | [MOL File]
247131-79-9.mol | [Molecular Weight]
505.587 |
Hazard Information | Back Directory | [Uses]
JTV-803 mesylate is a human factor Xa inhibitor with oral anticoagulant activity. JTV-803 exhibits competitive inhibition of human factor Xa, with a Ki value of 0.019μM and IC50Value is 0.081μM. JTV-803 is 100 times more selective at inhibiting human factor Xa than its comparator. JTV-803 is an effective oral anticoagulant for the prevention of thrombosis[1]. | [References]
[1] Antithrombotic effects of a synthetic inhibitor of activated factor X, JTV-803, in animals |
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