| Chemical Properties | Back Directory | [Boiling point ]
709.357±60.00 °C(Press: 760.00 Torr)(predicted) | [density ]
1.281±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) | [pka]
9.739±0.20(predicted) |
| Hazard Information | Back Directory | [Uses]
CDK2-IN-29 (Compound 13q) is an inhibitor for cyclin-dependent kinase (CDK), with IC50 of 96 nM and 360 nM, for CDK 2 and CDK 4, respectively[1]. | [IC 50]
CDK2: 96 nM (IC50); CDK4: 360 nM (IC50) | [References]
[1] Yue EW, et al., Synthesis and evaluation of indenopyrazoles as cyclin-dependent kinase inhibitors. 3. Structure activity relationships at C3(1,2). J Med Chem. 2002 Nov 21;45(24):5233-48. DOI:10.1021/jm0201722 |
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