| Identification | Back Directory | [Name]
Cyclopropanecarboxamide, N-[6-[3-[[[(2-methylpropyl)sulfonyl]amino]methyl]phenyl]-1H-indazol-3-yl]- | [CAS]
2471972-15-1 | [Synonyms]
Cyclopropanecarboxamide, N-[6-[3-[[[(2-methylpropyl)sulfonyl]amino]methyl]phenyl]-1H-indazol-3-yl]- | [Molecular Formula]
C22H26N4O3S | [MOL File]
2471972-15-1.mol | [Molecular Weight]
426.53 |
| Hazard Information | Back Directory | [Uses]
CDK-IN-14 (Compound 9) is a potent and selective CDKL2 (Cyclin-dependent kinase-like 2) inhibitor with an IC50 value of 460 nM. CDKL2 is involved in various biological processes such as tumorigenesis, development, and viral infections. CDK-IN-14 serves as a powerful tool for studying the biological functions of CDKL2 and holds promise for research in fields related to cancer, infections, and other diseases[1]. | [References]
[1] Bashore F M, et al. Discovery and Characterization of a Chemical Probe for Cyclin-Dependent Kinase-Like 2[J]. bioRxiv, 2024. DOI:10.1101/2024.05.12.593776 |
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