| Identification | Back Directory | [Name]
Butanoic-3,4,4,4-d4 acid, 3-(methyl-d3)-2-oxo-, sodium salt (1:1) | [CAS]
2483831-46-3 | [Synonyms]
Butanoic-3,4,4,4-d4 acid, 3-(methyl-d3)-2-oxo-, sodium salt (1:1)
α-Ketoisovaleric acid-[d7] sodium salt/Sodium 2-Keto-3-methyl-d3-butyrate-3,4,4,4-d4 | [Molecular Formula]
C5H9NaO3 | [MOL File]
2483831-46-3.mol | [Molecular Weight]
140.11 |
| Hazard Information | Back Directory | [Uses]
Sodium 3-methyl-2-oxobutanoate-d7 is the deuterium labeled Sodium 3-methyl-2-oxobutanoate[1]. Sodium 3-methyl-2-oxobutanoate is a precursor of pantothenic acid in Escherichia coli[2][3][4]. | [References]
[1] Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. DOI:10.1177/1060028018797110
[2] MAAS WK, et al. alpha-Ketoisovaleric acid, a precursor of pantothenic acid in Escherichia coli. J Bacteriol. 1953 Apr;65(4):388-93. DOI:10.1128/jb.65.4.388-393.1953
[3] Schauder P, et al. Oral administration of alpha-ketoisovaleric acid or valine in humans: blood kinetics and biochemical effects. J Lab Clin Med. 1984 Apr103(4):597-605. PMID:6366097
[4] Coitinho AS, et al. Pharmacological evidence that alpha-ketoisovaleric acid induces convulsions through GABAergic and glutamatergic mechanisms in rats. Brain Res. 2001 Mar 9894(1):68-73. DOI:10.1016/s0006-8993(00)03321-7 |
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