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2483831-79-2

2483831-79-2 Structure

2483831-79-2 Structure
IdentificationBack Directory
[Name]

Thiazolium, 3-[[4-amino-2-(methyl-d3)-5-pyrimidinyl]methyl]-4-methyl-5-(4,6,6-trihydroxy-4,6-dioxido-3,5-dioxa-4,6-diphosphahex-1-yl)-, chloride (1:1)
[CAS]

2483831-79-2
[Synonyms]

Vitamin B1 Pyrophosphate-d3
Thiazolium, 3-[[4-amino-2-(methyl-d3)-5-pyrimidinyl]methyl]-4-methyl-5-(4,6,6-trihydroxy-4,6-dioxido-3,5-dioxa-4,6-diphosphahex-1-yl)-, chloride (1:1)
[Molecular Formula]

C12H19ClN4O7P2S
[MOL File]

2483831-79-2.mol
[Molecular Weight]

460.76
Chemical PropertiesBack Directory
[CAS Number Unlabeled]

154-87-0
Hazard InformationBack Directory
[Uses]

Thiamine pyrophosphate-d3 is the deuterium labeled Thiamine pyrophosphate. Thiamine pyrophosphate is the coenzyme form of Vitamin B1 and is a required intermediate in the pyruvate dehydrogenase complex and the ketoglutarate dehydrogenase complex.
[References]

[1] Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. DOI:10.1177/1060028018797110
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