| Identification | Back Directory | [Name]
α-(Aminomethyl)-4-[2,3-bis(nitrooxy)propoxy]-N-thieno[2,3-c]pyridin-2-ylbenzeneacetamide | [CAS]
2489328-74-5 | [Synonyms]
ROCK-IN-6
α-(Aminomethyl)-4-[2,3-bis(nitrooxy)propoxy]-N-thieno[2,3-c]pyridin-2-ylbenzeneacetamide | [Molecular Formula]
C19H19N5O8S | [MOL File]
2489328-74-5.mol | [Molecular Weight]
477.45 |
| Chemical Properties | Back Directory | [Boiling point ]
759.4±60.0 °C(Predicted) | [density ]
1.507±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(Predicted) | [pka]
12.60±0.43(Predicted) |
| Hazard Information | Back Directory | [Uses]
ROCK-IN-6 is a potent and selectiveROCK2 inhibitor with an IC50 of 2.19 nM. ROCK-IN-6 is extracted from patent WO2021164351 A1, example 7, has the potential for glaucoma and retinal diseases research[1]. | [IC 50]
ROCK2: 2.19 nM (IC50) | [References]
[1] Shen wang et al. Nitrooxyderivative of rock kinase inhibitor. Patent WO2021164351 A1 |
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