| Chemical Properties | Back Directory | [Melting point ]
154 °C | [Boiling point ]
487.750±45.00 °C(Press: 760.00 Torr)(predicted) | [density ]
1.554±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) | [form ]
Solid | [pka]
6.187±0.48(predicted) | [color ]
Off-white to light yellow |
| Hazard Information | Back Directory | [Uses]
hPL-IN-2 (compound 2u) is a potent, reversible, and non-competitive inhibitor of pancreatic lipase (IC50: 1.63 μM) and can be used in anti-obesity research[1]. | [References]
[1] Zhao Y, et al. Design, synthesis and biological evaluation of salicylanilides as novel allosteric inhibitors of human pancreatic lipase. Bioorg Med Chem. 2023 Aug 15;91:117413.. DOI:10.1016/j.bmc.2023.117413 |
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