| Identification | Back Directory | [Name]
Benzamide, 4-[[cyclopropyl[(2,3,4,5-tetrafluorophenyl)sulfonyl]amino]methyl]-N-hydroxy- | [CAS]
2490284-18-7 | [Synonyms]
KT-531
Benzamide, 4-[[cyclopropyl[(2,3,4,5-tetrafluorophenyl)sulfonyl]amino]methyl]-N-hydroxy- | [Molecular Formula]
C17H14F4N2O4S | [MOL File]
2490284-18-7.mol | [Molecular Weight]
418.36 |
| Hazard Information | Back Directory | [Uses]
KT-531 is a potent and selective inhibitor of HDAC6 with an IC50 of 8.5 nM. KT-531 exhibits strong inhibition against SUP-T11 cells with an IC50 of 0.42 μM. KT-531 can be used in study hematological cancers[1]. | [References]
[1] Toutah K, et al. Development of HDAC Inhibitors Exhibiting Therapeutic Potential in T-Cell Prolymphocytic Leukemia. J Med Chem. 2021 Jun 24;64(12):8486-8509. DOI:10.1021/acs.jmedchem.1c00420 |
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