| Identification | Back Directory | [Name]
L-Histidine, glycyl-L-tyrosyl-L-histidyl-L-tyrosyl-L-α-glutamyl-L-arginyl-L-tryptophyl-L-isoleucyl- | [CAS]
2490442-13-0 | [Synonyms]
L-Histidine, glycyl-L-tyrosyl-L-histidyl-L-tyrosyl-L-α-glutamyl-L-arginyl-L-tryptophyl-L-isoleucyl- | [Molecular Formula]
C60H77N17O14 | [MOL File]
2490442-13-0.mol | [Molecular Weight]
1260.36 |
| Chemical Properties | Back Directory | [density ]
1.50±0.1 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted) | [pka]
2.88±0.10(predicted) | [Sequence]
Gly-Tyr-His-Tyr-Glu-Arg-Trp-Ile-His |
| Hazard Information | Back Directory | [Uses]
HBP08 is a selective inhibitor of CXCL12/HMGB1 interaction. HBP08 has a high affinity for HMGB1 (Kd=0.8 μM). HBP08 inhibits CXCL12-mediated cell migration[1]. | [References]
[1] Sgrignani J, et al. Systematic Development of Peptide Inhibitors Targeting the CXCL12/HMGB1 Interaction. J Med Chem. 2021 Sep 23;64(18):13439-13450. DOI:10.1021/acs.jmedchem.1c00852 |
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| Company Name: |
Fuan Bio
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| Tel: |
15002819872 |
| Website: |
fuanbio.com / www.fuanbio.com |
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