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2490676-18-9

2490676-18-9 Structure

2490676-18-9 Structure
IdentificationBack Directory
[Name]

2490676-18-9
[CAS]

2490676-18-9
[Synonyms]

FTX-6058
[Molecular Formula]

C22H18FN5O2
[MDL Number]

MFCD34567730
[MOL File]

2490676-18-9.mol
[Molecular Weight]

403.42
Chemical PropertiesBack Directory
[density ]

1.55±0.1 g/cm3(Predicted)
[storage temp. ]

Store at -20°C
[solubility ]

DMSO : 125 mg/mL (309.86 mM; Need ultrasonic)
[form ]

Solid
[pka]

3.07±0.20(Predicted)
[color ]

White to light yellow
Hazard InformationBack Directory
[Uses]

Pociredir (FTX-6058) is a potent and orally active inhibitor of Embryonic Ectoderm Development (EED). Pociredir can induce HbF protein expression in cell and murine models. Pociredir can be used for the research of select hemoglobinopathies, including sickle cell disease and β-thalassemia[1][2].
[storage]

Store at -20°C
[References]

[1] Boerner LK. Virtual meeting delivers first time drug structures. April 12, 2021.
[2] Fulcrum Therapeutics Presents Published Structure of Investigational Small Molecule FTX-6058 at the American Chemical Society (ACS) Spring 2021 Virtual Conference.
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