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2498658-13-0

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2498658-13-0 Structure

2498658-13-0 Structure

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[Name] Benzenesulfonamide, 4-[[7'-[(1R,2S)-2-hydroxy-2-methylcyclopentyl]-6'-oxospiro[cyclopropane-1,5'-[5H]pyrrolo[2,3-d]pyrimidine]-2'(7'H)-yl]amino]-N-(3-methyl-3-azetidinyl)-, rel-
[CAS] 2498658-13-0
[Synonyms] CDK2-IN-7 Benzenesulfonamide, 4-[[7'-[(1R,2S)-2-hydroxy-2-methylcyclopentyl]-6'-oxospiro[cyclopropane-1,5'-[5H]pyrrolo[2,3-d]pyrimidine]-2'(7'H)-yl]amino]-N-(3-methyl-3-azetidinyl)-, rel-
[Molecular Formula] C24H30N6O4S
[MOL File] 2498658-13-0.mol
[Molecular Weight] 498.6

Chemical Properties	Back Directory
[Boiling point ] 782.0±70.0 °C(Predicted)
[density ] 1.50±0.1 g/cm3(Predicted)
[pka] 8.23±0.20(Predicted)

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[Uses] CDK2-IN-7 is a CDK2 inhibitor for researching cancer (IC50 < 50 nM).
[IC 50] CDK2/cyclinE: 50 nM (IC₅₀)
[References] [1] Sabnis RW. Sulfonylamide Compounds as CDK2 Inhibitors for Treating Cancer. ACS Med Chem Lett. 2021 Sep 13;12(10):1528-1529. DOI:10.1021/acsmedchemlett.1c00471

2498658-13-0 suppliers list

Company Name:	TargetMol Chemicals Inc.
Telephone:	15002134094
Website:	https://www.targetmol.cn/

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