Identification | Back Directory | [Name]
2,6-Piperidinedione, 3-[6-[[1-[1-[(1-methylcyclobutyl)methyl]-4-piperidinyl]-1H-pyrazol-4-yl]methyl]-2-oxobenz[cd]indol-1(2H)-yl]- | [CAS]
2504233-73-0 | [Synonyms]
E3 ligase Ligand 21 2,6-Piperidinedione, 3-[6-[[1-[1-[(1-methylcyclobutyl)methyl]-4-piperidinyl]-1H-pyrazol-4-yl]methyl]-2-oxobenz[cd]indol-1(2H)-yl]- | [Molecular Formula]
C31H35N5O3 | [MOL File]
2504233-73-0.mol | [Molecular Weight]
525.64 |
Hazard Information | Back Directory | [Uses]
E3 ligase Ligand 21 (compound 2) is a cereblon binder for the degradation of Ikaros or Aiolos by the ubiquitin proteasome pathway[1]. | [IC 50]
Cereblon | [References]
[1] Gesine Kerstin VEITS, et al. Cereblon binders for the degradation of ikaros. WO2019191112A1. |
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