| Identification | Back Directory | [Name]
1-Piperazinecarboxylic acid, 4-[4-[[6-[[[(2,6-dichloro-3,5-dimethoxyphenyl)amino]carbonyl]methylamino]-4-pyrimidinyl]amino]phenyl]-, 1,1-dimethylethyl ester | [CAS]
2504949-83-9 | [Synonyms]
1-Piperazinecarboxylic acid, 4-[4-[[6-[[[(2,6-dichloro-3,5-dimethoxyphenyl)amino]carbonyl]methylamino]-4-pyrimidinyl]amino]phenyl]-, 1,1-dimethylethyl ester | [Molecular Formula]
C29H35Cl2N7O5 | [MOL File]
2504949-83-9.mol | [Molecular Weight]
632.54 |
| Chemical Properties | Back Directory | [Boiling point ]
794.7±60.0 °C(Predicted) | [density ]
1.365±0.06 g/cm3(Predicted) | [form ]
Solid | [pka]
11.02±0.70(Predicted) | [color ]
Light yellow to yellow |
| Hazard Information | Back Directory | [Uses]
Infigratinib-Boc is a derivative of Infigratinib containing a Boc (t-Butyloxy carbonyl) group. Infigratinib is an ATP-competitive pan-FGFR inhibitor[1]. | [References]
[1] Guangyan Du, et al. Discovery of a Potent Degrader for Fibroblast Growth Factor Receptor 1/2. Angew Chem Int Ed Engl. 2021 Jul 12;60(29):15905-15911. DOI:10.1002/anie.202101328 |
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