| Identification | Back Directory | [Name]
2,4-Dimethyldiphenylamine | [CAS]
25078-04-0 | [Synonyms]
N-PHENYL-2,4-XYLIDINE
PHENYL(2,4-XYLYL)AMINE
2,4-DIMETHYLDIPHENYLAMINE
2,4-DiMethyl-N-phenylaniline
2,4-DiMethyl-N-phenylbenzenaMine
N-Phenyl-2,4-xylidine
Phenyl(2,4-xylyl)amine
TRIS(4-BROMOPHENYL)2,4-DIMETHYL DIPHENYLAMINE | [EINECS(EC#)]
677-190-2 | [Molecular Formula]
C14H15N | [MDL Number]
MFCD08275461 | [MOL File]
25078-04-0.mol | [Molecular Weight]
197.28 |
| Chemical Properties | Back Directory | [Melting point ]
43°C | [Boiling point ]
170°C 3mm | [density ]
1.049±0.06 g/cm3(Predicted) | [Fp ]
0°C | [storage temp. ]
Keep in dark place,Inert atmosphere,Room temperature | [solubility ]
soluble in Methanol | [form ]
powder to lump | [pka]
1.11±0.40(Predicted) | [color ]
White to Yellow | [InChI]
InChI=1S/C14H15N/c1-11-8-9-14(12(2)10-11)15-13-6-4-3-5-7-13/h3-10,15H,1-2H3 | [InChIKey]
BWYYRZBQXLCZJL-UHFFFAOYSA-N | [SMILES]
C1(NC2=CC=CC=C2)=CC=C(C)C=C1C |
| Hazard Information | Back Directory | [Chemical Properties]
white crystalline. | [Uses]
2,4-Dimethyldiphenylamine is mainly used in organic synthesis and pharmaceutical intermediates. | [Synthesis]
GENERAL STEPS: A solution of potassium tert-butoxide (KOtBu, 102.1 mg, 1.3 eq.) and complex 3a (10-50 mL, 0.01-0.05 mol, prepared from 4.6 mg of complex 3a dissolved in 1.0 mL of dichloromethane) was added to a Schlenk reaction tube under nitrogen atmosphere. The reaction tube was sealed and the solvent was removed under reduced pressure. Toluene (0.5 mL), 2,4-dimethylaniline (0.84 mmol) and chlorobenzene (0.70 mmol) were then added sequentially. The reaction mixture was stirred vigorously at the indicated temperature for 3 to 24 hours. Upon completion of the reaction, the solvent was removed under reduced pressure and the residue was purified by silica gel column chromatography to afford the target product 2,4-dimethyldiphenylamine. | [References]
[1] Advanced Synthesis and Catalysis, 2008, vol. 350, # 5, p. 652 - 656
[2] Tetrahedron, 2017, vol. 73, # 52, p. 7308 - 7314 |
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