| Identification | Back Directory | [Name]
Carbamic acid, N-[6-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]hexyl]-, 1,1-dimethylethyl ester | [CAS]
2509093-23-4 | [Synonyms]
Thalidomide-4-O-C6-NHBoc
1,1-Dimethylethyl N-[6-[[2-(2,6-Dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]hexyl]carbamate
Carbamic acid, N-[6-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]hexyl]-, 1,1-dimethylethyl ester | [Molecular Formula]
C24H31N3O7 | [MOL File]
2509093-23-4.mol | [Molecular Weight]
473.52 |
| Chemical Properties | Back Directory | [Boiling point ]
692.9±55.0 °C(Predicted) | [density ]
1.269±0.06 g/cm3(Predicted) | [form ]
Solid | [pka]
10.70±0.40(Predicted) | [color ]
Off-white to light yellow |
| Hazard Information | Back Directory | [Uses]
Thalidomide-O-C6-NHBoc is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology[1]. | [IC 50]
Cereblon | [References]
[1] Daniel A. HARKI, et al. Compounds that degrade kinases and uses thereof. WO2020247537A1.
[2] Zhang NN, et al. A Thermostable mRNA Vaccine against COVID-19. Cell. 2020;182(5):1271-1283.e16. DOI:10.1016/j.cell.2020.07.024 |
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| Company Name: |
Bide Pharmatech Ltd.
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| Telephone: |
400-1647117 13681763483 |
| Website: |
https://www.bidepharm.com/ |
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