| Chemical Properties | Back Directory | [density ]
1.373±0.10 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) | [form ]
Solid | [pka]
12.020±0.20(predicted) | [color ]
Light yellow to yellow |
| Hazard Information | Back Directory | [Uses]
(R)-NVS-ZP7-4 is the R-isomer of NVS-ZP7-4. NVS-ZP7-4 is a Zinc transporter SLC39A7 (ZIP7) inhibitor that is also the first reported chemical tool to probe the impact of modulating ER zinc levels and investigate ZIP7 as a novel agentgable node in the Notch pathway. | [References]
[1] Nolin E, et al. Discovery of a ZIP7 inhibitor from a Notch pathway screen. Nat Chem Biol. 2019 Feb;15(2):179-188. DOI:10.1038/s41589-018-0200-7 |
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