ChemicalBook--->CAS DataBase List--->2517935-02-1

2517935-02-1

2517935-02-1 Structure

2517935-02-1 Structure
IdentificationBack Directory
[Name]

Fazpilodemab
[CAS]

2517935-02-1
[Synonyms]

Fazpilodemab
Research Grade Fazpilodemab (DHC88101)
Chemical PropertiesBack Directory
[form ]

Liquid
[color ]

Colorless to light yellow
Hazard InformationBack Directory
[Uses]

Fazpilodemab (BFKB8488A) is a humanized, agonistic, bispecific antibody targeting fibroblast growth factor receptor 1c (FGFR1c) and Klothoβ. Fazpilodemab can be used for the research of type 2 diabetes mellitus (T2DM) or nonalcoholic fatty liver disease (NAFLD)[1].
[IC 50]

FGFR1c; Klothoβ
[References]

[1] Wong C, et al. Fibroblast growth factor receptor 1/Klothoβ agonist BFKB8488A improves lipids and liver health markers in patients with diabetes or NAFLD: A phase 1b randomized trial. Hepatology. 2022 Aug 22. DOI:10.1002/hep.32742
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