| Identification | Back Directory | [Name]
2H-1-Benzopyran-2-one, 4-[[1-[(5-hydroxy-4-oxo-4H-pyran-2-yl)methyl]-1H-1,2,3-triazol-4-yl]methoxy]- | [CAS]
2525175-90-8 | [Synonyms]
Tyrosinase-IN-5
2H-1-Benzopyran-2-one, 4-[[1-[(5-hydroxy-4-oxo-4H-pyran-2-yl)methyl]-1H-1,2,3-triazol-4-yl]methoxy]- | [Molecular Formula]
C18H13N3O6 | [MOL File]
2525175-90-8.mol | [Molecular Weight]
367.31 |
| Hazard Information | Back Directory | [Uses]
Tyrosinase-IN-5 (compound 16c) is a potent inhibitor of tyrosinase with an IC50 of 0.02 μM. Tyrosinase-IN-5 efficiently suppresses the melanogenesis without significant toxicity on cells[1]. | [References]
[1] Ashooriha M, et al. Kojic acid-natural product conjugates as mushroom tyrosinase inhibitors. Eur J Med Chem. 2020;201:112480. DOI:10.1016/j.ejmech.2020.112480 |
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