| Identification | Back Directory | [Name]
Z-Ile-Glu-Pro-Phe-OMe | [CAS]
252557-97-4 | [Synonyms]
CH 5450
Z-Ile-Glu-Pro-Phe-OMe
Z-ILE-GLU-PRO-PHE-CO2ME
Z-Ile-Glu-Pro-Phe-Ome, BR
CH-5450
(Z-Ile-Glu-Pro-Phe-CO2Me)
L-Phenylalanine, N-[(phenylmethoxy)carbonyl]-L-isoleucyl-L-α-glutamyl-L-prolyl-, 4-methyl ester | [Molecular Formula]
C34H44N4O9 | [MDL Number]
MFCD28167838 | [MOL File]
252557-97-4.mol | [Molecular Weight]
652.75 |
| Chemical Properties | Back Directory | [Boiling point ]
928.4±65.0 °C(Predicted) | [density ]
1.251±0.06 g/cm3(Predicted) | [form ]
Solid | [pka]
4.48±0.10(Predicted) | [color ]
White to off-white | [Sequence]
Z-Ile-Glu-Pro-Phe-OMe |
| Hazard Information | Back Directory | [Uses]
CH 5450 (Z-Ile-Glu-Pro-Phe-Ome) is a selective short peptide human cardiac chymase inhibitor. CH-5450 inhibits the action of rat MAB elastase 2 on substrate Ang I with an IC50 value of 49 μM and N-succinyl-Ala-Ala-Pro-Phe-p-nitroanilide with an IC50 value of 4.8 μM[1]. | [References]
[1] Carlos F Santos, et al. Kinetic characterization and inhibition of the rat MAB elastase-2, an angiotensin I-converting serine protease. Can J Physiol Pharmacol. 2002 Jan;80(1):42-7. DOI:10.1139/y02-004 |
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Musechem
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| Tel: |
+1-800-259-7612 |
| Website: |
www.musechem.com |
| Company Name: |
Ontores Biotech
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| Tel: |
0571-88760729 18072970094 |
| Website: |
www.ontoresinc.cn |
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