| Identification | Back Directory | [Name]
N-[(2-Methoxyphenyl)methyl]-N-(4-phenoxy-3-pyridinyl)acetamide | [CAS]
253307-65-2 | [Synonyms]
N-[(2-Methoxyphenyl)methyl]-N-(4-phenoxy-3-pyridinyl)acetamide | [Molecular Formula]
C21H20N2O3 | [MOL File]
253307-65-2.mol | [Molecular Weight]
348.4 |
| Chemical Properties | Back Directory | [Melting point ]
89-91 °C | [Boiling point ]
513.6±50.0 °C(Predicted) | [density ]
1.203±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(Predicted) | [form ]
Solid | [pka]
5.16±0.18(Predicted) | [color ]
Off-white to light yellow |
| Hazard Information | Back Directory | [Uses]
PBR28 is an TSPO modulator, which can be used for prevention research of Pulmonary Arterial Hypertension (PAH). PBR28 can be used to trace 18 KDa transporter (TSPO) by adding radioactive labeling, which plays an important role in brain positron emission tomography (PET) imaging studies[1]. | [References]
[1] Sander CY, et al. [11C]PBR28 radiotracer kinetics are not driven by alterations in cerebral blood flow. J Cereb Blood Flow Metab. 2021 Nov;41(11):3069-3084. DOI:10.1177/0271678X211023387 |
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