| Identification | Back Directory | [Name]
Pyrazolo[1,5-a]pyridine-3-carbonitrile, 6-(3-hydroxy-3-methyl-1-azetidinyl)-4-[6-[6-[(6-methoxy-3-pyridinyl)methyl]-3,6-diazabicyclo[3.1.1]hept-3-yl]-3-pyridinyl]- | [CAS]
2546116-88-3 | [Synonyms]
Pyrazolo[1,5-a]pyridine-3-carbonitrile, 6-(3-hydroxy-3-methyl-1-azetidinyl)-4-[6-[6-[(6-methoxy-3-pyridinyl)methyl]-3,6-diazabicyclo[3.1.1]hept-3-yl]-3-pyridinyl]- | [Molecular Formula]
C29H30N8O2 | [MOL File]
2546116-88-3.mol | [Molecular Weight]
522.6 |
| Hazard Information | Back Directory | [Uses]
Soxataltinib (example 7) is a potent inhibitor of RET-kinase, with the IC50 of 0.601 nM. Soxataltinib plays an important role in cancer research[1]. | [References]
[1] Shouyao Holdings (Beijing) Co., Ltd. Preparation of piperazine-containing pyrazolopyridine carbonitrile derivative as RET selective inhibitors for treatment of RET-related diseases. China, CN112209925 A 2021-01-12 |
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