| Identification | Back Directory | [Name]
(2,3-epoxyphytyl)menaquinone | [CAS]
25486-55-9 | [Synonyms]
C05849
2,3-Epoxide
VitaMin K Epox
Vitamin K1 Oxide
Vitamin K Epoxide
Phylloquinone Oxid
Vitamin K1 epoxide
Phylloquinone Oxide
PHYTONADIONE EPOXIDE
Vitamin K 2,3-epoxide
2,3-Epoxyphylloquinone
Vitamin K1 2,3-Epoxide
2,3-Epoxide Vitamin K1
Phylloquinone, epoxide
Phylloquinone-2,3-epoxide
(2,3-epoxyphytyl)menaquinone
2,3-Epoxide Vitamin K1 (Mixture of Diastereomers)
2,3-Epoxy-2,3-dihydro-2-methyl-3-phytyl-1,4-naphthoquinone
Phytonadione Impurity 8 (2,3-Epoxide Vitamin K1 )(Mixture of Diastereomers)
1,4-Naphthoquinone,2,3-epoxy-2,3-dihydro-2-methyl-3-phytyl-2,3-epoxyphylloquinone
1a-methyl-7a-(3,7,11,15-tetramethylhexadec-2-enyl)naphtho[2,3-b]oxirene-2,7-dione
1a,7a-Dihydro-1a-methyl-7a-(3,7,11,15-tetramethyl-2-hexadecenyl)naphth[2,3-b]oxirene-2,7-dione
1a,7a-Dihydro-1a-methyl-7a-(3,7,11,15-tetramethyl-2-hexadecen-1-yl)-naphth[2,3-b]oxirene-2,7-dione
1a,7a-Dihydro-1a-methyl-7a-(3,7,11,15-tetramethyl-2-hexadecen-1-yl)-naphth[2,3-β]oxirene-2,7-dione
Naphth[2,3-b]oxirene-2,7-dione, 1a,7a-dihydro-1a-methyl-7a-(3,7,11,15-tetramethyl-2-hexadecen-1-yl)-
1a-Methyl-7a-[(2Z)-3,7,11,15-tetramethylhexadec-2-en-1-yl]-1aH,2H,7H,7aH-naphtho[2,3-b]oxirene-2,7-dione
Naphth[2,3-B]oxirene-2,7-dione,1A,7A-dihydro-1A-methyl-7A-(3,7,11,15-tetramethyl-2-hexadecenyl)-phylloquinone oxide | [EINECS(EC#)]
247-022-9 | [Molecular Formula]
C31H46O3 | [MDL Number]
MFCD00870307 | [MOL File]
25486-55-9.mol | [Molecular Weight]
466.7 |
| Chemical Properties | Back Directory | [storage temp. ]
-20°C | [solubility ]
Chloroform (Sparingly), Ethyl Acetate (Slightly) | [Boiling point ]
561.1±50.0 °C(Predicted) | [density ]
1.019±0.06 g/cm3(Predicted) | [form ]
Oil | [color ]
Colourless to Pale Yellow Thick to | [Cosmetics Ingredients Functions]
SKIN PROTECTING
ASTRINGENT | [InChI]
InChI=1S/C31H46O3/c1-22(2)12-9-13-23(3)14-10-15-24(4)16-11-17-25(5)20-21-31-29(33)27-19-8-7-18-26(27)28(32)30(31,6)34-31/h7-8,18-20,22-24H,9-17,21H2,1-6H3 | [InChIKey]
KUTXFBIHPWIDJQ-UHFFFAOYSA-N | [SMILES]
O1C2(CC=C(C)CCCC(C)CCCC(C)CCCC(C)C)C(=O)C3=C(C(=O)C12C)C=CC=C3 |
| Hazard Information | Back Directory | [Description]
Vitamin K is a dietary nutrient essential for the normal biosynthesis of factors that are required for blood clotting. It has also been shown to inhibit cell growth. Vitamin K1 2,3-epoxide is the inactive metabolite of vitamin K1. During clotting, vitamin K1 is converted to this epoxide form and then rapidly reduced back to the vitamin by a microsomal epoxide reductase. This is referred to as the vitamin K epoxide cycle.1 Certain anticoagulants target clotting factor synthesis by inhibiting the recycling of vitamin K1 from the inactive epoxide.1 | [Chemical Properties]
Clear Colourless to Pale Yellow Oil | [Uses]
A metabolite of Vitamin K1 (V676080). | [Biochem/physiol Actions]
Vitamin K1 2,3-epoxide is a vitamin K derivative. It is a fat soluble vitamin produced by plants. Vitamin K is essential for blood coagulation. Vitamin K is rarely deficient in a human diet since it is continually recycled in our cells. Vitamin K 2,3-epoxide acts as a substrate for vitamin K 2,3-epoxide reductase (VKOR) complex. Elevated levels of serum vitamin K epoxide in patients is associated with familial multiple coagulation factor deficiency. | [storage]
Store at -20°C | [References]
[1] IA CHOONARA. The relationship between inhibition of vitamin K1 2,3-epoxide reductase and reduction of clotting factor activity with warfarin.[J]. British journal of clinical pharmacology, 1988, 25 1: 1-7. DOI: 10.1111/j.1365-2125.1988.tb03274.x |
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