| Identification | Back Directory | [Name]
Benzoic acid, 4-[5-(4-fluorophenyl)-1,5-dihydro-6-(tetrahydro-2H-pyran-4-yl)pyrrolo[2,3-f]indazol-7-yl]- | [CAS]
2555004-05-0 | [Synonyms]
A1AT modulator 2
Benzoic acid, 4-[5-(4-fluorophenyl)-1,5-dihydro-6-(tetrahydro-2H-pyran-4-yl)pyrrolo[2,3-f]indazol-7-yl]- | [Molecular Formula]
C27H22FN3O3 | [MOL File]
2555004-05-0.mol | [Molecular Weight]
455.48 |
| Chemical Properties | Back Directory | [Boiling point ]
631.1±55.0 °C(Predicted) | [density ]
1.42±0.1 g/cm3(Predicted) | [form ]
Solid | [pka]
4.20±0.10(Predicted) | [color ]
Off-white to light yellow |
| Hazard Information | Back Directory | [Uses]
A1AT modulator 2 (compound 33) is a modulator of A1AT (α-1 antitrypsin) with an IC50 value of ＞1.0 μM and an EC50 value of ＜0.4 μM. A1AT modulator 2 can be used for the research of infection and inflammation[1]. | [References]
[1] Bandarage, Upul Keerthi, et al. Pyrrolo[2,3-f]indazole derivatives as modulators of α-1 antitrypsin and their preparation. US20200361939. 2020. |
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