| Identification | Back Directory | [Name]
Butanamide, 4-amino-2-[[4,4-bis(3-methyl-2-thienyl)-3-buten-1-yl]methylamino]-N-[(2-chlorophenyl)methyl]- | [CAS]
2556833-68-0 | [Synonyms]
mGAT3/4-IN-2
Butanamide, 4-amino-2-[[4,4-bis(3-methyl-2-thienyl)-3-buten-1-yl]methylamino]-N-[(2-chlorophenyl)methyl]- | [Molecular Formula]
C26H32ClN3OS2 | [MOL File]
2556833-68-0.mol | [Molecular Weight]
502.13 |
| Hazard Information | Back Directory | [Uses]
mGAT3/4-IN-2 (compound 27b) is a potent mGAT3/mGAT4 inhibitor, with pIC50 values of 5.44 and 5.25, respectively[1]. | [References]
[1] Zar?ba P, et al. Novel mouse GABA uptake inhibitors with enhanced inhibitory activity toward mGAT3/4 and their effect on pain threshold in mice. Eur J Med Chem. 2020 Feb 15;188:111920. DOI:10.1016/j.ejmech.2019.111920 |
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