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25577-04-2

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25577-04-2 Structure

25577-04-2 Structure
IdentificationBack Directory
[Name]

1,6,7-Trihydroxyxanthone
[CAS]

25577-04-2
[Synonyms]

7-Trihydroxyxanthone
1,6,7-Trihydroxyxanthone
1,6,7-trihydroxyxanthen-9-one
1,6,7-Trihydroxy-9H-xanthen-9-one
9H-Xanthen-9-one, 1,6,7-trihydroxy-
[Molecular Formula]

C13H8O5
[MDL Number]

MFCD19441065
[MOL File]

25577-04-2.mol
[Molecular Weight]

244.2
Chemical PropertiesBack Directory
[storage temp. ]

2-8°C
Hazard InformationBack Directory
[Uses]

1,6,7-Trihydroxyxanthone is a potent anticancer agent. 1,6,7-Trihydroxyxanthone inhibits cell proliferation and induces cell Apoptosis. 1,6,7-Trihydroxyxanthone decreases Bmi-1 expressio and increases the protein levels expression of P14, P16[1].
[References]

[1] Fu WM, et al. MiR-218-targeting-Bmi-1 mediates the suppressive effect of 1,6,7-trihydroxyxanthone on liver cancer cells. Apoptosis. 2015 Jan;20(1):75-82. DOI:10.1007/s10495-014-1047-3
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