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2568523-72-6

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2568523-72-6 Structure

2568523-72-6 Structure

Identification	Back Directory
[Name] PROTAC SMARCA2 degrader-6
[CAS] 2568523-72-6
[Synonyms] PROTAC SMARCA2 degrader-6
[Molecular Formula] C56H70N12O5S
[MOL File] 2568523-72-6.mol
[Molecular Weight] 1023.3

Chemical Properties	Back Directory
[density ] 1.404±0.10 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
[pka] 6.274±0.30(predicted)

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[Uses] PROTAC SMARCA2 degrader-6 (compound I-427) is a PROTAC degrader targeting SMARCA2; it degrades SMARCA2 proteins in A549 cells with an DC50 <100 nM, and a maximum degradation rate (Dmax%) >90 after 24 h of treatment[1].
[References] [1] Preparation of heterocyclic compounds as SMARCA degraders and uses thereof. World Intellectual Property Organization, WO2020251971 A1 2020-12-17.

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Company Name:	TargetMol Chemicals Inc.
Tel:	15002134094
Website:	https://www.targetmol.cn/

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