ChemicalBook--->CAS DataBase List--->2569434-60-0

2569434-60-0

2569434-60-0 Structure

2569434-60-0 Structure
IdentificationBack Directory
[Name]

Research Grade Ulviprubart (DHK27701)
[CAS]

2569434-60-0
[Synonyms]

Ulviprubart
Research Grade Ulviprubart
Research Grade Ulviprubart (DHK27701)
Chemical PropertiesBack Directory
[form ]

Liquid
[color ]

Colorless to light yellow
Hazard InformationBack Directory
[Uses]

Ulviprubart (ABC-008) is a monoclonal antibody targeting the KLRG1 receptor that selectively depletes highly differentiated cytotoxic T cells. Ulviprubart can be used in the study of inclusion body myositis (IBM)[1].
[References]

[1] Brady S, et al. Inclusion body myositis: Correcting mitochondfrial and lysosomal autophagy impairment as a potential therapeutic strategy[J]. Autoimmunity Reviews, 2024: 103644. DOI:10.1016/j.autrev.2024.103644
[2] Konry T, et al., Single Cell Droplet-Based Efficacy and Transcriptomic Analysis of a Novel Anti-KLRG1 Antibody for Elimination of Autoreactive T Cells. Res Sq [Preprint]. 2024 Sep 8:rs.3.rs-4745216. DOI:10.21203/rs.3.rs-4745216/v1
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