| Identification | Back Directory | [Name]
Iseganan | [CAS]
257277-05-7 | [Synonyms]
Iseganan
L-Argininamide, L-arginylglycylglycyl-L-leucyl-L-cysteinyl-L-tyrosyl-L-cysteinyl-L-arginylglycyl-L-arginyl-L-phenylalanyl-L-cysteinyl-L-valyl-L-cysteinyl-L-valylglycyl-, cyclic (5→14),(7→12)-bis(disulfide) | [EINECS(EC#)]
-0 | [Molecular Formula]
C78H126N30O18S4 | [MOL File]
257277-05-7.mol | [Molecular Weight]
1900.29 |
| Hazard Information | Back Directory | [Uses]
Iseganan is an antimi crobial peptide intended for use in the reduction in the severity of oral mucositis; oral decontamination in ventilator-associated pneumonia; aerosol formulation for control of infections in patients with cystic fibrosis.
| [in vivo]
Iseganan (intraperitoneal injection; 200 and 400 μg per mouse; once) shows anti-parasite activity in T. crassiceps murine cysticercosis model[3]. | Animal Model: | Female BALB/cAnN mice injected with T. crassiceps[3] | | Dosage: | 200 and 400 μg per mouse | | Administration: | Intraperitoneal injection; 200 and 400 μg per mouse; once | | Result: | Reduced the parasite load by 25% when compared with the control group. |
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