ChemicalBook--->CAS DataBase List--->25743-12-8

25743-12-8

25743-12-8 Structure

25743-12-8 Structure
IdentificationBack Directory
[Name]

NH-(PEG2-OH)2
[CAS]

25743-12-8
[Synonyms]

NH-bis-PEG3
Hn(peg2-oh)2
NH-(PEG2-OH)2
NH-bis(PEG2-OH)
3,6,12,15-Tetraoxa-9-azaheptadecane-1,17-diol
[Molecular Formula]

C12H27NO6
[MDL Number]

MFCD29764330
[MOL File]

25743-12-8.mol
[Molecular Weight]

281.35
Chemical PropertiesBack Directory
[Boiling point ]

409.1±40.0 °C(Predicted)
[density ]

1.099±0.06 g/cm3(Predicted)
[pka]

14.06±0.10(Predicted)
Hazard InformationBack Directory
[Description]

NH-bis(PEG2-OH) is a small pEG reagent that can be used to conjugate with carboxylic acid in the presence of HATU or EDC
[Uses]

NH-bis-PEG3 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
[IC 50]

PEGs
[References]

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
Spectrum DetailBack Directory
[Spectrum Detail]

NH-(PEG2-OH)2(25743-12-8)1HNMR
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