| Identification | Back Directory | [Name]
2,5-Dioxopyrrolidin-1-yl 8-azidooctanoate | [CAS]
2576471-56-0 | [Synonyms]
2,5-Dioxopyrrolidin-1-yl 8-azidooctanoate
Octanoic acid, 8-azido-, 2,5-dioxo-1-pyrrolidinyl ester | [Molecular Formula]
C12H18N4O4 | [MOL File]
2576471-56-0.mol | [Molecular Weight]
282.3 |
| Hazard Information | Back Directory | [Uses]
8-Azido-octanoyl-OSu is a click chemistry reagent containing an azide group. Used as a building block to introduce 8-azidooctanoic acid (CAS 217180-76-2) fragment. This fragment is used for further modifications using Click-chemistry (CuAAC), as a protected aminogroup or is used in physico-chemical investigations[1]. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups. | [References]
[1] Jiang X, et al. Recent applications of click chemistry in drug discovery. Expert Opin Drug Discov. 2019 Aug;14(8):779-789. DOI:10.1080/17460441.2019.1614910 |
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