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2579696-45-8

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2579696-45-8 Structure

2579696-45-8 Structure
IdentificationBack Directory
[Name]

Methanesulfonamide, N-[3-[1-[(4-methylphenyl)methyl]-1H-benzimidazol-2-yl]phenyl]-
[CAS]

2579696-45-8
[Synonyms]

Antimicrobial agent-1
Methanesulfonamide, N-[3-[1-[(4-methylphenyl)methyl]-1H-benzimidazol-2-yl]phenyl]-
[Molecular Formula]

C22H21N3O2S
[MOL File]

2579696-45-8.mol
[Molecular Weight]

391.49
Chemical PropertiesBack Directory
[Boiling point ]

617.9±65.0 °C(Predicted)
[density ]

1.25±0.1 g/cm3(Predicted)
[pka]

8.01±0.10(Predicted)
Hazard InformationBack Directory
[Uses]

Antimicrobial agent-1 (compound 6C) possesses potent activity against TolC mutant E. coli with an MIC value of 2 μg/mL. Antimicrobial agent-1 and Colistin exhibit synergistic activity against Gram-negative bacteria. Antimicrobial agent-1 has no cytotoxicity on mammalian cell lines, with MICs > 128?μg/mL in Caco-2 and Vero cell lines[1].
[References]

[1] Dokla EME, et al. Development of benzimidazole-based derivatives as antimicrobial agents and their synergistic effect with colistin against gram-negative bacteria. Eur J Med Chem. 2020;186:111850. DOI:10.1016/j.ejmech.2019.111850
2579696-45-8 suppliers list
Company Name: TargetMol Chemicals Inc.  
Telephone: 15002134094
Website: https://www.targetmol.cn/
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