| Identification | Back Directory | [Name]
1H-Indole-2-carboxamide, 5-chloro-N-(8-ethyl-2-methyl-3-oxo-1-thia-4-azaspiro[4.5]dec-4-yl)-3-methyl- | [CAS]
2581825-57-0 | [Synonyms]
Influenza virus-IN-5 1H-Indole-2-carboxamide, 5-chloro-N-(8-ethyl-2-methyl-3-oxo-1-thia-4-azaspiro[4.5]dec-4-yl)-3-methyl- | [Molecular Formula]
C21H26ClN3O2S | [MOL File]
2581825-57-0.mol | [Molecular Weight]
419.97 |
| Hazard Information | Back Directory | [Uses]
Influenza virus-IN-5 (Compound 5f) is an inhibitor of influenza virus hemagglutinin (HA) with an EC50 of 1 nM against influenza A/H3N2 virus[1]. | [References]
[1] Cihan-üstünda? G, et al. Superior inhibition of influenza virus hemagglutinin-mediated fusion by indole-substituted spirothiazolidinones. Bioorg Med Chem. 2020 Jan 1;28(1):115130. DOI:10.1016/j.bmc.2019.115130 |
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