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2585648-55-9

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2585648-55-9 Structure

2585648-55-9 Structure
IdentificationBack Directory
[Name]

INDEX NAME NOT YET ASSIGNED
[CAS]

2585648-55-9
[Synonyms]

EEDi-5273
EEDi-5273 （APG-5918）
[Molecular Formula]

C26H22F4N6O2
[MOL File]

2585648-55-9.mol
[Molecular Weight]

526.5
Chemical PropertiesBack Directory
[density ]

1.55±0.1 g/cm3(Predicted)
[form ]

Solid
[pka]

1.42±0.20(Predicted)
[color ]

Light yellow to yellow
Hazard InformationBack Directory
[Uses]

EEDi-5273 is an exceptionally potent and orally efficacious EED inhibitor (IC50 = 0.2 nM) capable of achieving complete and persistent tumor regression.
[References]

[1] Rej RK, et al. Discovery of EEDi-5273 as an Exceptionally Potent and Orally Efficacious EED Inhibitor Capable of Achieving Complete and Persistent Tumor Regression. J Med Chem. 2021 Oct 14;64(19):14540-14556. DOI:10.1021/acs.jmedchem.1c01059
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