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25913-34-2

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25913-34-2 Structure

25913-34-2 Structure
IdentificationBack Directory
[Name]

ethyl 2-amino-6-benzyl-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxylate monohydrochloride
[CAS]

25913-34-2
[Synonyms]

Dimaten
Nonflamin
Tinoridine HCl
Einecs 247-342-9
Y-3642 hydrochloride
Tinoridine Hydrochloride
Tenolinidine hydrochloride
Tenocyclidine hydrochloride
Tinoridine Hydrochloride USP/EP/BP
Tenoridine Hydrochloride Impurities
Tinoridine hydrochloride Y-3642 hydrochloride
2-Amino-3-ethoxycarbonyl-6-benzyl-4,5,6,7-tetrahydrothieno[2,3-
2-Amino-3-ethoxycarbonyl-6-benzyl-4,5,6,7-tetrahydrothieno[2,3-c]pyridine hydrochloride
2-Amino-3-ethoxycarbonyl-6-benzyl-4,5,6,7-tetrahydrothieno(2,3-C)pyridine monohydrochloride
ethyl 2-amino-6-benzyl-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxylate monohydrochloride
2-Amino-6-benzyl-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxylic Acid Ethyl Ester Hydrochloride
ethyl 2-amino-6-benzyl-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxylate monohydrochloride USP/EP/BP
Thieno(2,3-C)pyridine-3-carboxylic acid, 4,5,6,7-tetrahydro-2-amino-6-benzyl-, ethyl ester, monohydrochloride
Thieno(2,3-C)pyridine-3-carboxylic acid, 2-amino-4,5,6,7-hexahydro-6-(phenylmethyl)-, ethyl ester, monohydrochloride
Thieno[2,3-c]pyridine-3-carboxylic acid, 2-aMino-4,5,6,7-tetrahydro-6-(phenylMethyl)-, ethyl ester, Monohydrochloride
[EINECS(EC#)]

247-342-9
[Molecular Formula]

C17H21ClN2O2S
[MDL Number]

MFCD01680536
[MOL File]

25913-34-2.mol
[Molecular Weight]

352.879
Chemical PropertiesBack Directory
[Melting point ]

234-235° (dec)
[storage temp. ]

Keep in dark place,Inert atmosphere,Room temperature
[solubility ]

DMSO : ≥ 31 mg/mL (87.85 mM)
[form ]

Solid
[color ]

White to yellow
Safety DataBack Directory
[Symbol(GHS) ]

Exclamation Mark (GHS07)
GHS07
[Signal word ]

Warning
[Hazard statements ]

H302
[Precautionary statements ]

P264-P270-P301+P312-P330-P501
[Toxicity]

LD50 orally in mice: 1601 mg/kg (Nakanishi, 1974)
Hazard InformationBack Directory
[Uses]

Tinoridine hydrochloride is a nonsteroidal anti-inflammatory agent and also has potent radical scavenger and antiperoxidative activity.
[Definition]

ChEBI: Tinoridine hydrochloride is a thienopyridine.
[in vivo]

CCl4 aministration produces a marked decrease in the concentrations of liver microsomal cytochrome P-450 and G6Pase, indicating that hepatic endoplasmic reticulum function is disrupted. Prior treatment of the animals with tinoridine (100 mg/kg) significantly reduces the CCl4-induced alterations in the enzyme activities, and a rapid recovery toward the normal values is observed[2].

[References]

[1] O Shimada, et al. Hydroxyl radical scavenging action of tinoridine. Agents Actions. 1986 Nov;19(3-4):208-14.
[2] Yasuda H, et al. The protective effect of tinoridine against carbon tetrachloride hepatotoxicity. Toxicol Appl Pharmacol. 1980 Mar 15;52(3):407-13. DOI:10.1016/0041-008x(80)90335-x
Spectrum DetailBack Directory
[Spectrum Detail]

ethyl 2-amino-6-benzyl-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxylate monohydrochloride(25913-34-2)1HNMR
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