| Identification | Back Directory | [Name]
5-(4-CHLOROPHENYL)-2 4-DIHYDRO-1 2 4-TR& | [CAS]
26028-65-9 | [Synonyms]
Chlorophenyltriazolethiol
5-(p-chlorophenyl)-s-triazole-3-thio
5-(p-chlorophenyl)-s-triazole-3-thiol
s-Triazole-3-thiol, 5-(p-chlorophenyl)-
5-(4-CHLOROPHENYL)-2 4-DIHYDRO-1 2 4-TR&
3-(4-Chlorophenyl)-1,2,4-triazole-5-thiol
3-Mercapto-5-(p-chloro-phenyl)-s-triazole
5-(p-Chlorophenyl)-1,2,4-triazole-3-thiol
5-(4-Chloro-phenyl)-1H-[1,2,4]triazole-3-thiol
4H-1,2,4-triazole-3-thiol, 5-(4-chlorophenyl)-
5-(4-Chlorophenyl)-2,4-dihydro-[1,2,4]-triazole-3-thiol
5-(4-chloro-phenyl)-1,2-dihydro-[1,2,4]triazole-3-thione
3H-1,2,4-Triazole-3-thione, 5-(4-chlorophenyl)-1,2-dihydro-
5-(4-Chlorophenyl)-2,4-dihydro-[1,2,4]-triazole-3-thione 97%
5-(4-Chlorophenyl)-2,4-dihydro-[1,2,4]-triazole-3-thione | [Molecular Formula]
C8H6ClN3S | [MDL Number]
MFCD00174362 | [MOL File]
26028-65-9.mol | [Molecular Weight]
211.67 |
| Chemical Properties | Back Directory | [Melting point ]
295-299 °C(lit.) | [Boiling point ]
296.8±42.0 °C(Predicted) | [density ]
1.55±0.1 g/cm3(Predicted) | [form ]
solid | [pka]
8.21±0.20(Predicted) | [color ]
White to light yellow | [InChI]
InChI=1S/C8H6ClN3S/c9-6-3-1-5(2-4-6)7-10-8(13)12-11-7/h1-4H,(H2,10,11,12,13) | [InChIKey]
NHEHIODVWGKDFV-UHFFFAOYSA-N | [SMILES]
N1C(C2=CC=C(Cl)C=C2)=NC(=S)N1 |
| Hazard Information | Back Directory | [Uses]
DCN1-UBC12-IN-4 (compound 5p) is an inhibitor of DCN1-UBC12, with an IC50 greater than 10000 nM, and it exhibits anti-tumor activity[1]. | [Definition]
ChEBI: 5-(4-chlorophenyl)-1,2-dihydro-1,2,4-triazole-3-thione is a member of triazoles. | [References]
[1] Wenjuan Zhou, et al. Development of phenyltriazole thiol-based derivatives as highly potent inhibitors of DCN1-UBC12 interaction. Eur J Med Chem. 2021 May 5:217:113326. DOI:10.1016/j.ejmech.2021.113326 |
|
| Company Name: |
Energy Chemical
|
| Tel: |
021-021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
| Company Name: |
Sigma-Aldrich
|
| Tel: |
021-61415566 800-8193336 |
| Website: |
https://www.sigmaaldrich.cn |
|