| Identification | Back Directory | [Name]
UCB7362 | [CAS]
2610631-17-7 | [Synonyms]
UCB7362
Benzamide, N-[3-[(4S)-2-amino-1,4,5,6-tetrahydro-4-methyl-6-oxo-1-[(2R,4R)-tetrahydro-2-methyl-2H-pyran-4-yl]-4-pyrimidinyl]-2-chlorophenyl]-3-cyano- | [Molecular Formula]
C25H26ClN5O3 | [MOL File]
2610631-17-7.mol | [Molecular Weight]
479.96 |
| Hazard Information | Back Directory | [Uses]
(2R,4R)-UCB7362 is the (2R,4R) isomer of UCB7362 (HY-151568). UCB7362 is an inhibitor of plasma proteinase X (PMX) with antimalarial activity[1]. | [References]
[1] Lowe MA, et al. Discovery and Characterization of Potent, Efficacious, Orally Available Antimalarial Plasmepsin X Inhibitors and Preclinical Safety Assessment of UCB7362. J Med Chem. 2022 Oct 10. DOI:10.1021/acs.jmedchem.2c01336 |
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