| Identification | Back Directory | [Name]
UCB7362 hydrochloride | [CAS]
2610631-18-8 | [Synonyms]
UCB7362 hydrochloride
UCB7362 hydrochloride(2610631-17-7 Free base) |
| Hazard Information | Back Directory | [Uses]
(2R,4R)-UCB7362 hydrochloride is the (2R,4R) isomer of UCB7362 (HY-151568). (2R,4R)-UCB7362 hydrochloride is an inhibitor of plasma proteinase X (PMX) with antimalarial activity[1]. | [References]
[1] Lowe MA, et al. Discovery and Characterization of Potent, Efficacious, Orally Available Antimalarial Plasmepsin X Inhibitors and Preclinical Safety Assessment of UCB7362. J Med Chem. 2022 Oct 27;65(20):14121-14143. DOI:10.1021/acs.jmedchem.2c01336 |
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