| Identification | Back Directory | [Name]
1H-Pyrrolo[3,4-g]isoquinoline-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-5,6,7,8-tetrahydro-, hydrochloride (1:1) | [CAS]
2616553-33-2 | [Synonyms]
Androgen receptor degrader-2
2-(2,6-Dioxopiperidin-3-yl)-5,6,7,8-tetrahydro-1H-pyrrolo[3,4-g]isoquinoline-1,3(2H)-dione hydrochloride
1H-Pyrrolo[3,4-g]isoquinoline-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-5,6,7,8-tetrahydro-, hydrochloride (1:1) | [Molecular Formula]
C16H16ClN3O4 | [MOL File]
2616553-33-2.mol | [Molecular Weight]
349.77 |
| Hazard Information | Back Directory | [Uses]
Thalidomide-(2)piperidine (compound 9) is a potent E3 ligase ligand. Thalidomide-(2)piperidine can be used for synthesis of PROTACs[1]. | [IC 50]
Cereblon | [References]
[1] Shao MW, et, al. Androgen receptor protein degraders with a tricyclic cereblon ligand. WO2021231927A1. |
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