| Identification | Back Directory | [Name]
5-bromo-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione | [CAS]
26166-92-7 | [Synonyms]
135586
5-bromo-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione
1H-Isoindole-1,3(2H)-dione, 5-bromo-2-(2,6-dioxo-3-piperidinyl)-
5-bromo-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione(WXC07613)
5-bromo-2-(2,6-dioxopiperidin-3-yl)-2,3-dihydro-1 H-isoindole-1,3-dione | [Molecular Formula]
C13H9BrN2O4 | [MDL Number]
MFCD30188073 | [MOL File]
26166-92-7.mol | [Molecular Weight]
337.13 |
| Chemical Properties | Back Directory | [Melting point ]
>230 °C | [Boiling point ]
564.3±45.0 °C(Predicted) | [density ]
1.794±0.06 g/cm3(Predicted) | [storage temp. ]
Inert atmosphere,Room Temperature | [form ]
Solid | [pka]
10.60±0.40(Predicted) | [color ]
Off-white to gray | [InChI]
InChI=1S/C13H9BrN2O4/c14-6-1-2-7-8(5-6)13(20)16(12(7)19)9-3-4-10(17)15-11(9)18/h1-2,5,9H,3-4H2,(H,15,17,18) | [InChIKey]
MWMSBQXTHIEBNT-UHFFFAOYSA-N | [SMILES]
C1(=O)C2=C(C=C(Br)C=C2)C(=O)N1C1CCC(=O)NC1=O |
| Hazard Information | Back Directory | [Description]
5-Bromo-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione is a derivative of thalidomide with an bromide atom on the benzyl ring | [Chemical Properties]
White to Light gray to Light yellow powder to crystal | [Uses]
Thalidomide-5-Br (compound 4) is a compound with a bromodomain. Thalidomide-5-Br can be used in the research of inflammation, tumor and neurology[1]. | [References]
[1] Yeung, et al. "Novel thalidomide analogues with potent NFκB and TNF expression inhibition." MedChemComm 2.11 (2011): 1073-1078. |
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