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26195-65-3

26195-65-3 Structure

26195-65-3 Structure
IdentificationBack Directory
[Name]

N-[(S)-5,6,7,9-Tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo[a]heptalen-7-yl]-2,2,2-trifluoroacetamide
[CAS]

26195-65-3
[Synonyms]

NSC 305987
N-Deacetyl-N-(trifluoroacetyl)colchicine
2,2,2-trifluoro-N-[(7S)-1,2,3,10-tetramethoxy-9-oxo-6,7-dihydro-5H-benzo[a]heptalen-7-yl]acetamide
N-[(S)-5,6,7,9-Tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo[a]heptalen-7-yl]-2,2,2-trifluoroacetamide
2,2,2-Trifluoro-N-[(7S)-5,6,7,9-tetrahydro-1,2,3,10-tetraMethoxy-9-oxobenzo[a]heptalen-7-yl]acetaMide
Acetamide, 2,2,2-trifluoro-N-[(7S)-5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo[a]heptalen-7-yl]-
[Molecular Formula]

C22H22F3NO6
[MOL File]

26195-65-3.mol
[Molecular Weight]

453.41
Chemical PropertiesBack Directory
[Boiling point ]

681.3±55.0 °C(Predicted)
[density ]

1.36±0.1 g/cm3(Predicted)
[pka]

9.68±0.40(Predicted)
Hazard InformationBack Directory
[Chemical Properties]

Faintly Yellow Crystalline Powder
[Uses]

An antimitotic agent that disrupts microtubles by binding to tubulin and preventing its polymerization. Stimulates the intrinsic GTPase activity of tubulin. Induces apoptosis in several normal and t umor cell lines and activates the JNK/SAPK signaling pathway.
[Uses]

An antimitotic agent that disrupts microtubles by binding to tubulin and preventing its polymerization. Stimulates the intrinsic GTPase activity of tubulin. Induces apoptosis in several normal and tumor cell lines and activates the JNK/SAPK signaling pathway.
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