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2629960-35-4

2629960-35-4 Structure

2629960-35-4 Structure
IdentificationBack Directory
[Name]

GPER activator 1
[CAS]

2629960-35-4
[Synonyms]

GPER activator 1
[Molecular Formula]

C17H14ClFN2O2S
[MOL File]

2629960-35-4.mol
[Molecular Weight]

364.82
Chemical PropertiesBack Directory
[Boiling point ]

521.867±50.00 °C(Press: 760.00 Torr)(predicted)
[density ]

1.468±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
[pka]

6.589±0.50(predicted)
Hazard InformationBack Directory
[Uses]

GPER activator 1 (compound 6-26) is a GPER-selective compound without cytotoxicity. GPER activator 1 exhibits dual inhibition of TNFα- and IL-6-induced inflammation[1].
[References]

[1] Bhuwan Prasad Awasthi, et al. G Protein-Coupled Estrogen Receptor-Mediated Anti-Inflammatory and Mucosal Healing Activity of a Trimethylpyridinol Analogue in Inflammatory Bowel Disease. J Med Chem.2024 Jul 11;67(13):10601-10621. DOI:10.1021/acs.jmedchem.3c02458
2629960-35-4 suppliers list
Company Name: TargetMol Chemicals Inc.  
Tel: 15002134094
Website: https://www.targetmol.cn/
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