| Identification | Back Directory | [Name]
Benzonitrile, 2-[4-[4-(aminomethyl)-1,2-dihydro-1-oxo-6-phthalazinyl]-1-methyl-1H-pyrazol-5-yl]-4-chloro-6-(cyclopropyloxy)-3-fluoro-, (2S)- | [CAS]
2630904-44-6 | [Synonyms]
(S)-MRTX-1719
MRTX1719 (P/S-)
Benzonitrile, 2-[4-[4-(aminomethyl)-1,2-dihydro-1-oxo-6-phthalazinyl]-1-methyl-1H-pyrazol-5-yl]-4-chloro-6-(cyclopropyloxy)-3-fluoro-, (2S)- | [Molecular Formula]
C23H18ClFN6O2 | [MOL File]
2630904-44-6.mol | [Molecular Weight]
464.89 |
| Hazard Information | Back Directory | [Uses]
(S)-Navlimetostat (example 16-7) is the S-enantiomer of Navlimetostat. (S)-Navlimetostat is a PRMT5/MTA complex inhibitor, with an IC50 of 7070 nM[1]. | [IC 50]
PRMT5 | [storage]
Store at -20°C | [References]
[1] Thomas P. BOBINSKI, et al. Mta-cooperative prmt5 inhibitors. WO2021050915A1. |
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