| Identification | Back Directory | [Name]
Phenol, 4,4'-(1-phenyl-4-propyl-1H-pyrazole-3,5-diyl)bis- | [CAS]
263717-32-4 | [Synonyms]
Estrogen receptor-agonist-1
4,4′-(1-Phenyl-4-propyl-1H-pyrazole-3,5-diyl)bis[phenol]
Phenol, 4,4'-(1-phenyl-4-propyl-1H-pyrazole-3,5-diyl)bis- | [Molecular Formula]
C24H22N2O2 | [MOL File]
263717-32-4.mol | [Molecular Weight]
370.44 |
| Chemical Properties | Back Directory | [Melting point ]
240-245 °C | [Boiling point ]
585.2±50.0 °C(Predicted) | [density ]
1.18±0.1 g/cm3(Predicted) | [form ]
Solid | [pka]
9.05±0.15(Predicted) |
| Hazard Information | Back Directory | [Uses]
Estrogen receptor-agonist-1 (compound 4e) is a estrogen receptor (ER) agonist that binds to ERα with high affinity[1]. | [IC 50]
ERα | [References]
[1] Stauffer SR, et al. Pyrazole ligands: structure-affinity/activity relationships and estrogen receptor-alpha-selective agonists. J Med Chem. 2000 Dec 28;43(26):4934-47. DOI:10.1021/jm000170m |
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