2640109-42-6

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2640109-42-6 Structure

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[Name] M1/M2/M4 muscarinic agonist 1
[CAS] 2640109-42-6
[Synonyms] M1/M2/M4 muscarinic agonist 1

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[Uses] M1/M2/M4 muscarinic agonist 1 (Compound 42) is a muscarinic M4/M1/M2 agonist with EC50 values of 6.5, 26 and 210 nM for M4/M1/M2, respectively. M1/M2/M4 muscarinic agonist 1 can be used for research on mental diseases, such as schizophrenia, delusion, etc[1].
[IC 50] mAChR1: 26 nM (EC₅₀); mAChR2: 210 nM (EC₅₀); mAChR4: 6.5 nM (EC₅₀)
[References] [1] Christopher G Thomson, et al. Transaminases Provide Key Chiral Building Blocks for the Synthesis of Selective M1/M4 Agonists. ACS Med. Chem. Lett. 2023. Nov 6.

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