| Chemical Properties | Back Directory | [Boiling point ]
555.057±50.00 °C(Press: 760.00 Torr)(predicted) | [density ]
1.536±0.10 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) | [solubility ]
DMSO: 2 mg/mL, clear | [form ]
Solid | [pka]
0.623±0.60(predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
CCT374705 is an orally active BCL6 inhibitor with potent antiproliferative effects in vitro. CCT374705 effectively inhibits tumor growth in a lymphoma xenograft mouse model[1]. | [References]
[1] Harnden AC, et al. Discovery of an In Vivo Chemical Probe for BCL6 Inhibition by Optimization of Tricyclic Quinolinones. J Med Chem. 2023 Apr 27;66(8):5892-5906. DOI:10.1021/acs.jmedchem.3c00155 |
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