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LPH-5 is a selective 5-HT2A receptor agonist (EC50=190 nM). LPH-5 works by selectively activating the 5-HT2A receptor, which may be involved in regulating mood, perception, and other central nervous system functions associated with the 5-HT2A receptor. LPH-5 can be used to further explore the 5-HT2A receptor in psychiatric disorders, including depression, anxiety, and substance abuse disorders[1]. | [References]
[1] M. Ro?rsted E, et al. Discovery and Structure–Activity Relationships of 2, 5-Dimethoxyphenylpiperidines as Selective Serotonin 5-HT2A Receptor Agonists[J]. Journal of Medicinal Chemistry, 2024. DOI:10.1021/acs.jmedchem.4c00082 |
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Biorbyt Ltd.
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http://www.biorbyt.com |
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