| Identification | Back Directory | [Name]
INDEX NAME NOT YET ASSIGNED | [CAS]
2647914-09-6 | [Synonyms]
(9H-fluoren-9-yl)methyl ((6S,9S)-1-amino-6-((4-(hydroxymethyl)phenyl)carbamoyl)-9-isopropyl-1,8,11,14,17-pentaoxo-2,7,10,13,16-pentaazaoctadecan-18-yl)carbamate | [Molecular Formula]
C39H48N8O9 | [MOL File]
2647914-09-6.mol | [Molecular Weight]
772.86 |
| Chemical Properties | Back Directory | [Boiling point ]
1190.0±65.0 °C(Predicted) | [density ]
1.314±0.06 g/cm3(Predicted) | [form ]
Solid | [pka]
10.61±0.46(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
Fmoc-Gly3-Val-Cit-PAB is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. | [IC 50]
Protease Cleavable Linker; Cleavable Linker | [References]
[1] Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337. DOI:10.1038/nrd.2016.268 |
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